节目是一档城市美食探索综艺，本季专注“烧烤”主题，由苏醒、杜海涛两位“饭搭子”作为本季主MC，前往深圳、武汉、淄博等六座城市，与好友共同打野当地特色烧烤、分享美食故事，体验城市真实烟火气，也寻找美食之间的情感共鸣。
每年日本申请专利的新品种食材多达千种，《头号食谱》节目组将挖掘这些新品类食材，并邀请全国知名大厨为新食材首创一道食谱，最终将由美食评审团现场试吃点评，选出每期神奇食材的"头号食谱"。 There is a huge number of ingredients in the world. What we usually eat is just a small part of them… In this show, great chefs cook unknown ingredients that they have never seen. The ingredient looks/tastes strange. The chef is firstly surprised at such an unknown, but gradually grasps ...
