Marco (Mario Casas) is a young businessman who manages one of the most successful technological companies in the world, ALVA, which has just launched its latest prototype into the market - CYCLONE, an electric car propelled by turbines that turn wind into energy. His friend and classmate Diego works with him, along with the latter's wife, Bárbara, the efficient marketing manager of the company. Eva, a young, ambitious engineer who has a lot to hide, also joins the team, and she will disrupt the balance at work, both emotionally and professionally, between the two business partners. In spite of being a popular guy, Marco, unlike Diego, doesn't have an exciting social life. He is a solitary man, and no one has access to the intimacy of his soul, apart from his psychologist, SARA, on whom he is emotionally dependent. Marco is haunted by a huge number of ghosts from his past and, although he tries hard to scare them away, he only finds comfort in sport and in frequenting a private club. People go there just to get pleasure and give free reign to their wildest erotic fantasies, without fear of falling in love, as everyone has to wear a mask to hide their faces. But everything changes when Marco meets Carol, the new educational psychologist who looks after his brother José, an 18-year-old boy with problems of autism, with whom he has a difficult relationship. With her, he will also meet his worst enemy - himself. Thanks to her, he will discover that it is never too late to love, even if it brings some pain along with it.
电影《七十二家房客》轰动一时，著名粤剧演员文觉非在电影里扮演的大反派“太子炳”深入民心，其余的经典角色如“三六九”等也脍炙人口，里面的一些台词更成为广东地区的流行俗语。而周星驰也在他的作品《功夫》里对《七十二家房客》的主场景和主要角色进行了艺术加工，向这部经典影片致敬。 新改编的《七十二家房客》主要讲述解放前40年代里广州西关一栋三层楼的大杂院里，“包租公”太子炳、“包租婆”八姑和七十多家房客交织所发生的许多妙趣横生、让人忍俊不禁又发人深省的故事。
城市保安哥张浩（张浩 饰）在家乡父老二龙湖村民面前虚荣吹牛，为了圆谎不得不变身商业奇才，携“巨额投资”带着团队衣锦还乡，遇上研究生毕业一心投入家乡建设致力乡村振兴的青梅竹马李茗菡，天差地别的两个人因初心、做事风格、教育程度等差异，在东北农村这个独特的背景下，碰撞出接二连三的喜剧包袱。作为全村的希望，张浩阴差阳错地成了全村共同的“鸡娃”对象。同时，求成心切又缺乏商业思维和经验的张浩自然而然的也成了诈骗分子的“盘中餐”。
